Increasing incidence of metastatic prostate cancer in the United States (2004-2013)
Increasing incidence of metastatic prostate cancer in the United States (2004-2013)
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DOI：
10.1038/pcan.2016.30
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发表时间：
2016-12-01
影响因子：
4.8
通讯作者：
Schaeffer, E. M.
中科院分区：
文献类型：
--
作者：
Weiner, A. B.;Matulewicz, R. S.;Schaeffer, E. M.
背景：美国前列腺癌筛查做法的变化导致近期总体发病率下降，但尚不清楚宽松的筛查是否导致诊断时晚期和转移性前列腺癌的发病率发生变化。方法：我们在美国 1089 个不同医疗机构的国家癌症数据库（2004-2013 年）中确定了所有诊断患有前列腺癌的男性。使用 Joinpoint 回归来模拟前列腺癌发病率相对于 2004 年分期的年度百分比变化 (APC)。 结果：从 2007 年到 2013 年，转移性前列腺癌的年发病率有所增加（Joinpoint 回归：APC：7.1%，P
BACKGROUND: Changes in prostate cancer screening practices in the United States have led to recent declines in overall incidence, but it is unknown whether relaxed screening has led to changes in the incidence of advanced and metastatic prostate cancer at diagnosis.METHODS: We identified all men diagnosed with prostate cancer in the National Cancer Data Base (2004-2013) at 1089 different health-care facilities in the United States. Joinpoint regressions were used to model annual percentage changes (APCs) in the incidence of prostate cancer based on stage relative to that of 2004.RESULTS: The annual incidence of metastatic prostate cancer increased from 2007 to 2013 (Joinpoint regression: APC: 7.1%, P