CRYSTAL-STRUCTURES OF POLYMORPHS-I AND III OF SULFATHIAZOLE
CRYSTAL-STRUCTURES OF POLYMORPHS-I AND III OF SULFATHIAZOLE
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DOI：
10.1107/s0567740872002183
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发表时间：
1972-01-01
期刊：
影响因子：
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通讯作者：
GAFNER, G
中科院分区：
文献类型：
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作者：
KRUGER, GJ;GAFNER, G
[GJ KRUGER和G. GAFNER化学物理小组，国家物理研究实验室，科学与工业研究委员会，邮政邮箱395，比勒陀利亚，南非（1971年3月11日收到）。另外两种已知的磺胺噻唑（N'-2-噻唑基磺胺）晶体结构现已确定并报道。利用Mo K~辐射和自动衍射仪测量了辐射强度。利用Karle-Hauptman~ 2关系对结构进行了求解，并用全矩阵最小二乘法对结构进行了细化。硫唑多晶型的主要区别在于氢键及其对晶体中分子排列的影响。
B¥ GJ KRUGER AND G. GAFNER Chemical Physics Group, National Physical Research Laboratory, Council Jbr Scientific & Industrial Research, PO Box 395, Pretoria, South Africa (Received 11 March 1971) The crystal structure of sulphathiazole II is known. The crystal structures of the other two known crystalline forms of sulphathiazole (N'-2-thiazolylsulphanilamide) have now been determined and are reported. The intensities were measured using Mo K~ radiation and an automatic diffractometer. The structures were solved by the application of the Karle-Hauptman~ 2 relationship and refinement was done by full-matrix least-squares methods. The main differences between the polymorphs of sulphathia-zole lie in the hydrogen bonding and its effects on the arrangement of the molecules in the crystals.