A new method to characterize the translation initiation sites of messenger ribonucleic acids.

A new method to characterize the translation initiation sites of messenger ribonucleic acids.
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表征信使核糖核酸翻译起始位点的新方法。

DOI:
10.1021/bi00266a031
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发表时间:
1982
期刊:
影响因子:
2.9
通讯作者:
ClarkJr,JM
ClarkJr,JM
中科院分区:
生物学3区
文献类型:
--
作者:
Pease,JR;Leung,DW;ClarkJr,JM

文献摘要

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0.78,实际上与Levi和Szabo(1982)为他们的一个模型计算的四个酪氨酸的超快运动的平均值一致[见Levi和Szabo(1982)表I的第二列]。一个紧凑的蛋白质分子与一个单一的酪氨酸将需要测试分子动力学的预测。这似乎是一个值得的事业,因为用这种方法分析蛋白质的快速运动提供了相当大的希望,它的一些基本预测的实验验证将扩大其范围,并增加其应用的信心。
0.78, virtually coincides with the average value resultingfrom the ultrafast motion of the four tyrosines calculated by Levi & Szabo (1982) for one of their models [see second column of Table I of Levi & Szabo (1982)]. A compact protein molecule with a single tyrosine will be required to test the predictions of molecular dynamics. This appears as a worthwhile undertaking because the analysis of the fast motions of proteins by this method offers considerable promise, and an experimental verification of some of its basic predictions would enlarge its scope and increase confidence in its application.