Surface plasmon resonance interferometer for bio- and chemical-sensors
Surface plasmon resonance interferometer for bio- and chemical-sensors
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DOI：
10.1016/s0030-4018(97)00726-8
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发表时间：
1998-05-01
影响因子：
2.4
通讯作者：
Nikitin, PI
中科院分区：
文献类型：
--
作者：
Kabashin, AV;Nikitin, PI
提出并通过实验实现了一种干涉测量方法，用于检测表面等离子共振（SPR）条件下由于折射率变化而引起的反射光相移。该方法对折射率变化Delta n 的灵敏度阈值估计为4X10(-8)。所提出的 SPR 干涉仪提供空间相位分辨率，因此能够考虑 SPR 支撑膜表面折射率分布的特性。它可以成功地应用于生物和化学传感器系统。 (C) 1998 Elsevier Science B.V. 保留所有权利。
An interferometric method for the detection of the phase shifts of reflected light under Surface Plasmon Resonance (SPR) conditions due to refractive index changes is proposed and experimentally realized. The sensitivity threshold of the method to a refractive index variation Delta n is estimated to be 4X10(-8). The proposed SPR-interferometer provides spatial phase resolution and thus enables to take into account the peculiarities of refractive index distribution over the surface of an SPR-supporting film. It can be successfully applied in bio- and chemical-sensor systems. (C) 1998 Elsevier Science B.V. All rights reserved.