The Anthracycline Antibiotics: New Directions in Drug Development and Cancer Treatment

The Anthracycline Antibiotics: New Directions in Drug Development and Cancer Treatment
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蒽环类抗生素:药物开发和癌症治疗的新方向

DOI:
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发表时间:
1983
期刊:
影响因子:
--
通讯作者:
M. Rozencweig
M. Rozencweig
中科院分区:
--
文献类型:
--
作者:
F. Muggia;M. Rozencweig

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蒽环类抗生素柔红霉素和阿霉素已成为当前抗癌治疗的主要成分。由于它们的重要性在20世纪60年代被引入临床试验时被认识到,因此出现了对实验室和临床结果的彻底审查。1971年在意大利米兰举行的阿霉素国际研讨会的会议记录总结了早期的发现[1]。随后,随着对这两种母体化合物的治疗作用和局限性的认识,法国、意大利、日本、苏联和美国等多个国家的制药企业开展了对其他蒽环类衍生物的广泛研究。这些新的研究趋势已经成为最近评论的主题[2],也是以卷[3,4]出版的会议和研讨会的主题。
The anthracycline antibiotics daunorubicin and doxorubicin, have become major components of current anticancer treatment. Because of their importance recognized upon their introduction into clinical trials in the 1960s, thorough reviews of laboratory and clinical findings have appeared. The proceedings of an International Symposium on Adriamycin held in Milan, Italy, 1971 were published summarizing early findings [1]. Subsequently, as the therapeutic impact as well as the limitations of the two parent compounds became appreciated, an extensive search for other anthracycline derivatives was carried out in pharmaceutical enterprises throughout various countries including France, Italy, Japan, the Soviet Union, and the United States. These new research trends have been the subject of more recent reviews [2], and also conferences and symposia published as volumes [3, 4].
DOI: 10.1007/bf00256709
发表时间: 1983
影响因子: 3
作者:
Yagoda,A
通讯作者: Yagoda,A
实验性阿霉素皮肤毒性的药理学解毒剂:β-肾上腺素能化合物的建议作用。
DOI: --
发表时间: 1981
期刊: Cancer treatment reports
影响因子: --
作者:
Dorr,RT;Alberts,DS
通讯作者: Alberts,DS
DOI: 10.1182/blood.v58.6.1203.bloodjournal5861203
发表时间: 1981-12
期刊: Blood
影响因子: 20.3
作者:
K. Rai;J. Holland;O. Glidewell;V. Weinberg;K. Brunner;JP Obrecht;H. Preisler;IW Nawabi;D. Pr
通讯作者: K. Rai;J. Holland;O. Glidewell;V. Weinberg;K. Brunner;JP Obrecht;H. Preisler;IW Nawabi;D. Pr