Remission, recovery, relapse, and recurrence in eating disorders:: Conceptualization and illustration of a validation strategy
Remission, recovery, relapse, and recurrence in eating disorders:: Conceptualization and illustration of a validation strategy
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DOI：
10.1002/jclp.2013
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发表时间：
2002-07-01
影响因子：
3
通讯作者：
Treasure, J
中科院分区：
文献类型：
--
作者：
Kordy, H;Kr채mer, B;Treasure, J
在建立共识的过程中，来自 19 个欧洲国家的专家组（COST 行动 86）根据 Frank 等人描述的抑郁症原则，调整了部分和完全缓解、复发、康复和复发等术语。德国 TR-EAT 项目的 233 名厌食症患者和 422 名暴食症患者（根据 DSM-IIIR 诊断）的治疗后过程的纵向数据说明了操作化的经验有效性。这些数据是在入院后 2.6 年使用纵向间隔随访评估 (LIFE) 收集的，并通过生存分析进行统计探索。事实证明，这些共识定义衡量了他们想要衡量的内容。它们打开了纵向视角，人们不仅可以了解患者是否会发生变化，还可以了解患者何时以及以何种概率发生变化。数据表明，症状持续改善对厌食症和神经性贪食症有不同的影响。例如，在关键症状缓解后的约 4 个月内，预防复发对于贪食症患者最为有益，而对于厌食症患者来说，这则不太重要。讨论了这种纵向方法是否以及如何有助于为有针对性的个体化治疗提供基于经验的基本原理。 (C) 2002 年 Wiley 期刊公司
In a consensus-building process a group of experts from 19 European countries (COST Action 86) adapted the terms partial and full remission, relapse, recovery, and recurrence according to principles described by Frank et al, for depression. The empirical validity of the operationalizations was illustrated by longitudinal data on the post treatment course of 233 anorectic and 422 bulimic patients (diagnosed according to DSM-IIIR) from the German Project TR-EAT. These data were collected 2,6 years after admission using the Longitudinal Interval Follow-up Evaluation (LIFE) and statistically explored by survival-analysis. It was demonstrated that these consensus definitions measure what they intend to measure, They open a longitudinal perspective in that one can learn not only whether, but also when and with what probability patients change for the better or worse. Data suggest that persistence of symptom improvement has different implications for anorexia and bulimia nervosa. For example, relapse prevention would be most beneficial for bulimic patients for about 4 months after key symptoms remit, while this would be of less importance for anorexic patients. It is discussed whether and how this longitudinal approach can contribute to an empirically based rationale for targeted and individualized treatment. (C) 2002 Wiley Periodicals, Inc.