Peripapillary retinal blood flow in normal tension glaucoma
Peripapillary retinal blood flow in normal tension glaucoma
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DOI：
10.1136/bjo.83.4.466
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发表时间：
1999-04-01
影响因子：
4.1
通讯作者：
Martin, B
中科院分区：
文献类型：
--
作者：
Chung, HS;Harris, A;Martin, B
目的：通过共聚焦扫描激光多普勒血流仪（cSLDF；“海德堡视网膜血流仪”）测量，确定正常张力性青光眼（NTG）患者与年龄匹配的对照组在乳头周围视网膜的血流方面是否存在差异。方法：12名NTG患者和12名年龄匹配的对照组使用(a)从鼻和颞部乳头周围视网膜采集的10 x 10像素盒（仪器默认样本量），(b)其中两个像素盒的平均值，以及(c)乳头周围视网膜内的每个合格像素进行比较。结果：使用放置在颞部或鼻乳头周围视网膜的单个10 x 10像素盒的默认样本测量的患者和对照组的血流量没有差异，或表示为这两个盒子的平均值。然而，在使用乳头周围视网膜每个像素的直方图中，NTG患者显示出明显更高的最小流量像素百分比(定义为小于一个任意流量单位：30% v 19%， p
Aims-To determine if normal tension glaucoma (NTG) patients differ from age matched controls in blood flow to the peripapillary retina, as measured with confocal scanning laser Doppler flowmetry (cSLDF; "Heidelberg retinal floumetry").Methods-12 NTG patients and 12 age matched controls were compared using (a) 10 x 10 pixel boxes (the instrument default sample size), taken from the nasal and temporal peripapillary retina, (b) the average from two of these boxes, and (c) every qualifying pixel within the peripapillary retina.Results-Patients and controls did not differ in blood flow measured using the default sample from a single 10 x 10 pixel box, placed in either the temporal or nasal peripapillary retina, or expressed as the average from these two boxes. However, in histograms using every pixel from the peripapillary retina, NTG patients displayed significantly higher percentages of minimal flow pixels (defined as less than one arbitrary unit of flow: 30% v 19%, p