Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.

Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells.
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培养肝癌细胞中诱导型酪氨酸转氨酶合成的转录后控制的进一步证据。

DOI:
10.1038/newbio239009a0
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发表时间:
1972
期刊:
Nature: New biology
影响因子:
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通讯作者:
Lyle Dethlefsen
Lyle Dethlefsen
中科院分区:
--
文献类型:
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作者:
Gordon M. Tomkins;Barbara Levinson;John D. Baxter;Lyle Dethlefsen;Lyle Dethlefsen

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有证据表明,RNA合成抑制剂放线菌素D抑制诱导性酪氨酸转氨酶的去诱导作用并非由于其抑制酶降解,从而支持了诱导酶的转录后控制模型。
The posttranscriptional control model for inducible enzymes is supported by evidence that the action of the RNA synthesis inhibitor, actinomycin D, in inhibiting the deinduction of inducible tyrosine aminotransferase is not due to its inhibition of enzyme degradation.