Captopril in the treatment of the elderly hypertensive patient.
Captopril in the treatment of the elderly hypertensive patient.
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卡托普利治疗老年高血压患者。
DOI：
10.1001/archinte.1985.00360110099022
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发表时间：
1985
影响因子：
--
通讯作者：
G. Dreslinski
中科院分区：
文献类型：
--
作者：
A. Jenkins;J. R. Knill;G. Dreslinski
作为一项大型多中心监测研究的一部分，975名65岁或以上的高血压患者接受了治疗，其中418人接受了至少12个月的药物治疗。血压从193/105 +/- 30/16（平均值+/- SD）降至159/88 +/- 25/12 mm Hg，副作用很少。治疗期间，大多数患者的肾功能未受干扰。临床上明显的呕吐发作的频率与总研究人群中的频率没有差异，表明在该年龄组中，尽管血压降低，但脑灌注仍得以维持。提示开搏通可用于老年高血压患者的治疗。
As part of a large multicenter surveillance study of captopril, 975 hypertensive patients aged 65 years or older were treated, 418 of whom received the drug for at least 12 months. Blood pressure was lowered from an entry level of 193/105 +/- 30/16 (mean +/- SD) to 159/88 +/- 25/12 mm Hg, and side effects were infrequent. During treatment, renal function was undisturbed in the majority of patients. The frequency of clinically evident hypotensive episodes did not differ from that found in the total study population, suggesting that in this age group, despite the reduction in blood pressure, cerebral perfusion was maintained. This experience suggests that captopril can be used for the treatment of the elderly hypertensive patient.
卡托普利治疗高血压后的自主神经和压力反射功能。
影响因子：
4.8
作者：
Warren,SE;O'Connor,DT;Cohen,IM
通讯作者：
Cohen,IM