THE MURINE T-CELL RECEPTOR USES A LIMITED REPERTOIRE OF EXPRESSED V-BETA GENE SEGMENTS
THE MURINE T-CELL RECEPTOR USES A LIMITED REPERTOIRE OF EXPRESSED V-BETA GENE SEGMENTS
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DOI：
10.1038/316517a0
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发表时间：
1985-01-01
期刊：
影响因子：
64.8
通讯作者：
HOOD, L
中科院分区：
文献类型：
--
作者：
BARTH, RK;KIM, BS;HOOD, L
Only 10 different V.beta. gene segments were found when the sequences of variable (V.beta.) genes of the mouse T-cell receptor were examined. The total number of expressed V.beta. gene segments may be 21 or fewer, which makes the expressed germline V.beta. repertoire much smaller than that of the IgH heavy chain or light chain genes. .beta.-Chain somatic diversification is concentrated at the V.beta.-D.beta.-J.beta. junctions.
