Structure and Chemical Characteristics of Dehydro-L-Ascorbic Acid in Solutions.
Structure and Chemical Characteristics of Dehydro-L-Ascorbic Acid in Solutions.
复制标题
溶液中脱氢-L-抗坏血酸的结构和化学特性。
DOI：
--
复制
发表时间：
1998
期刊：
影响因子：
--
通讯作者：
T. Kurata
中科院分区：
文献类型：
--
作者：
Y. Nishikawa;T. Kurata
L-抗坏血酸（ASA）作为电子供体在食品和生物系统中发挥着重要作用，在供电子过程中，ASA本身一般会被氧化为脱氢-L-抗坏血酸（DHA）。在水溶液中DHA的结构被再次证实为一水合双环结构。还阐明DHA在甲醇和乙醇溶液中具有溶剂化的双环结构，在这些情况下，通过C2羰基的溶剂化形成对映体。当这些溶剂化的双环DHA溶解在水中时，溶剂化的C2羰基上的溶剂分子很容易被水分子取代。根据MOPAC计算结果，估计C2水合双环DHA的生成热为-299.2kcal/mol，并且表明DHA通过水合而相当稳定。此外，表明双环DHA比ASA具有更紧凑和更少极性的结构。
L-Ascorbic acid (ASA) plays an important role in food and biological systems as an electron donor, and in the electron-donating process, ASA itself is generally oxidized to dehydro-L-ascorbic acid (DHA). The structure of DHA was reconfirmed to be monohydrated bicyclic structure in an aqueous solution. It was also clarified that DHA had the solvated bicyclic structure in methanol and ethanol solutions, and in these cases, the enantiomers were formed by the solvation of the C2 carbonyl group. When these solvated bicyclic DHA were dissolved in water, the solvent molecule on the solvated C2 carbonyl group was very easily replaced with a water molecule. From the results of MOPAC calculations, the heat of formation of C2 hydrated bicyclic DHA was estimated to be -299.2 kcal/mol, and DHA was clarified to be considerably stabilized by hydration. Furthermore, it was indicated that bicyclic DHA had more compact and less polar structure than ASA.
抗坏血酸对晶状体晶状体蛋白进行位点特异性糖化。
DOI：
10.1016/0304-4165(92)90081-5
发表时间：
1992
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Ortwerth,BJ;Slight,SH;Prabhakaram,M;Sun,Y;Smith,JB
通讯作者：
Smith,JB
运输抗坏血酸和其他水溶性维生素。
DOI：
10.1016/0304-4157(88)90014-7
发表时间：
1988
期刊：
Biochimica et biophysica acta
影响因子：
--
作者：
Rose,RC
通讯作者：
Rose,RC