Ionizing radiations in pregnancy and teratogenesis - A review of literature
Ionizing radiations in pregnancy and teratogenesis - A review of literature
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DOI：
10.1016/j.reprotox.2005.04.004
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发表时间：
2005-09-01
影响因子：
3.3
通讯作者：
Clementi, M
中科院分区：
文献类型：
--
作者：
De Santis, M;Di Gianantonio, E;Clementi, M
本文综述了有关产前辐射暴露对致畸效应评价的文献资料。我们特别关注母体电离辐射暴露对胎儿的影响，包括诊断性和职业性，特别是在先天性异常和出生体重方面。电离辐射可能是胎儿的致畸物，但已发现这种风险取决于剂量和与暴露时胎龄相关的影响。最近，特别值得注意的事实是，母亲甲状腺暴露于诊断性辐射与出生体重轻微下降有关。在怀孕期间无意中接触到的诊断程序通常不会增加先天性异常的自然风险，但会造成相当大的产妇焦虑状态。除非不能通过其他技术获得信息，否则孕妇应避免使用放射诊断程序。(c) 2005爱思唯尔公司版权所有。
The present paper is a review of the data available in the literature concerning the prenatal exposure to radiation evaluating the reported teratogenic effect. We have particularly focused on the fetal effects of maternal ionising radiation exposure, both diagnostic and occupational, particularly in terms of congenital anomalies and birth weight. Ionising radiation represents a possible teratogen for the fetus, but this risk has been found to be dependent on the dosage and the effects correlatable to the gestational age at exposure. Recently, of particularly note is the fact that maternal thyroid exposure to diagnostic radiation has been associated with a slight reduction in the birth weight. Inadvertent exposure from diagnostic procedures in pregnancy doesn't usually increase the natural risk of congenital anomalies but creates a considerable state of maternal anxiety. Diagnostic radiological procedures should be avoided in pregnant women unless the information cannot be obtained by other techniques. (c) 2005 Elsevier Inc. All rights reserved.