Palladium-catalyzed Decarbonylative Alkynylation of Aromatic Esters
Palladium-catalyzed Decarbonylative Alkynylation of Aromatic Esters
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DOI：
10.1246/cl.161001
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发表时间：
2017-02
影响因子：
1.6
通讯作者：
Toshimasa Okita;Kazushi Kumazawa;Ryosuke Takise;K. Muto;K. Itami;Junichiro Yamaguchi
中科院分区：
文献类型：
--
作者：
Toshimasa Okita;Kazushi Kumazawa;Ryosuke Takise;K. Muto;K. Itami;Junichiro Yamaguchi
报道了一种钯催化的芳香酯与末端炔烃的脱羰基化反应。该反应允许无卤素的Sonogashira偶联，得到各种芳基和杂芳基炔烃。通过正交偶联反应验证了该反应的实用性。
A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.