Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice.
Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice.
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DOI：
10.7554/elife.72440
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发表时间：
2022-07-13
期刊：
影响因子：
7.7
通讯作者：
Bastin, Julien
中科院分区：
文献类型：
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作者：
Cecchi, Romane;Vinckier, Fabien;Hammer, Jiri;Marusic, Petr;Nica, Anca;Rheims, Sylvain;Trebuchon, Agnes;Barbeau, Emmanuel J.;Denuelle, Marie;Maillard, Louis;Minotti, Lorella;Kahane, Philippe;Pessiglione, Mathias;Bastin, Julien
识别与选择不一致相关的波动因素是理性决策理论的一个主要问题。在这里，我们研究了情绪波动可能会使人类选择行为产生偏差的神经计算机制。脑内EEG数据收集在一个大的主题组（n=30），而他们正在执行交错的测验和选择任务，旨在研究一系列无关的反馈如何影响安全和危险的选择之间的决定。神经基线活动之前的选择发病面临的第一个情绪水平，估计的计算模型集成的反馈中收到的测验任务，然后到选项属性的权重，在计算模型预测风险的选择任务的态度。结果表明：（1）腹内侧前额叶皮层（vmPFC）和背侧前额叶皮层（daIns）的宽带γ活动（BGA）分别是情绪高涨和情绪低落的信号期;（2）vmPFC和daIns BGA的增加分别通过加重收益和损失前景来促进和缓和风险承担。因此，偶然的反馈会诱导大脑产生与不同情绪相对应的状态，并使对风险选项的评估产生偏差。更一般地说，这些发现可能解释了为什么在生活的某些部分经历积极（或消极）结果的人倾向于期望在任何其他方面取得成功（或失败）。
Identifying factors whose fluctuations are associated with choice inconsistency is a major issue for rational decision theory. Here, we investigated the neuro-computational mechanisms through which mood fluctuations may bias human choice behavior. Intracerebral EEG data were collected in a large group of subjects (n=30) while they were performing interleaved quiz and choice tasks that were designed to examine how a series of unrelated feedbacks affect decisions between safe and risky options. Neural baseline activity preceding choice onset was confronted first to mood level, estimated by a computational model integrating the feedbacks received in the quiz task, and then to the weighting of option attributes, in a computational model predicting risk attitude in the choice task. Results showed that (1) elevated broadband gamma activity (BGA) in the ventromedial prefrontal cortex (vmPFC) and dorsal anterior insula (daIns) was respectively signaling periods of high and low mood, (2) increased vmPFC and daIns BGA respectively promoted and tempered risk taking by overweighting gain vs. loss prospects. Thus, incidental feedbacks induce brain states that correspond to different moods and bias the evaluation of risky options. More generally, these findings might explain why people experiencing positive (or negative) outcome in some part of their life tend to expect success (or failure) in any other.