ARE ALL BORN EQUAL - INCIDENCE OF FEBRILE CONVULSIONS BY SEASON OF BIRTH

ARE ALL BORN EQUAL - INCIDENCE OF FEBRILE CONVULSIONS BY SEASON OF BIRTH
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DOI:
10.1136/bmj.284.6316.624
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发表时间:
1982-01-01
影响因子:
105.7
通讯作者:
GARDNER, A
GARDNER, A
中科院分区:
医学1区
文献类型:
--
作者:
SUNDERLAND, R;CARPENTER, RG;GARDNER, A

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为了检验出生季节是否对随后的疾病经历有影响,我们收集了1973年至1977年出生的所有谢菲尔德儿童的详细资料,这些儿童在2岁生日前因第一次热性惊厥入院。在连续28天队列中按出生日期进行的分析显示,在不同月份队列中,热性惊厥的发生率范围为2.5/1000例活产至30.2/1000例。统计学显着变化的发病率与季节和出生年份。这意味着,即使是大规模的流行病学研究,仅限于在特定的一周或一个月出生的儿童可能不代表整个儿童人口。
To test whether the season of birth had an effect on subsequent experience of illness, details were obtained of all Sheffield children born between 1973 and 1977 who were admitted to hospital before their 2nd birthday with a first febrile convulsion. Analysis by date of birth in consecutive 28 day cohorts showed that the incidence of febrile convulsions ranged from 2.5/1000 live births to 30.2/1000 in different month cohorts. Statistically significant variations were noted in the incidence rates in relation to season and year of birth. The implications is that even large scale epidemiological studies which have been confined to children born in a particular week or month may not be representative of the whole child population.