NECROTIZING ENTEROCOLITIS IN THE PREMATURE INFANT
NECROTIZING ENTEROCOLITIS IN THE PREMATURE INFANT
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DOI：
10.1148/83.5.879
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发表时间：
1964-01-01
期刊：
影响因子：
19.7
通讯作者：
BLANC, WA
中科院分区：
文献类型：
--
作者：
BERDON, WE;GROSSMAN, H;BLANC, WA
X线及病理结果显示小肠扩张，浆膜下及粘膜下层有气泡，门静脉可能充满空气。钡灌肠模式模仿无神经节巨结肠可能被证明。单次或多次穿孔合并气腹是常见的。小肠结肠炎的病因不明;没有严重的血管闭塞或既往肠梗阻。推测细菌内毒素在产生这种病变的作用。气泡是基本坏死性小肠结肠炎的一个标志，就像游离空气或门静脉空气一样，而不是疾病本身。如果在局部发现，则可能提示可手术切除的局部病变;不幸的是，大多数患者会死于败血症。
Roentgenographic and pathologic findings reveal the intestine dilated with gas bubbles in the subserosa and submucosa; the portal vein may be air-filled. A barium-enema pattern mimicking aganglionic megacolon may be demonstrated. Single and multiple perforations with pneumoperitoneum are common. The enterocolitis is of unknown etiology; gross vascular occlusion or prior intestinal obstruction has been absent. Speculations on the role of bacterial endotoxin in producing such lesions are presented. The air bubbles are a sign, as is the free air or portal-vein air, of the basic necrotizing enterocolitis, and not a disease per se. If noted locally, they may indicate a surgically resectable localized lesion; unfortunately most patients will die of sepsis.