Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic
Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic
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DOI：
10.1136/gutjnl-2020-321829
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发表时间：
2020-09-01
期刊：
影响因子：
24.5
通讯作者：
Cammarota, Giovanni
中科院分区：
文献类型：
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作者：
Ianiro, Gianluca;Mullish, Benjamin H.;Cammarota, Giovanni
COVID-19大流行导致SARS-CoV-2感染和相关死亡人数呈指数级增长，对医疗保健专业人员和设施构成重大挑战。个别国家已采取多项预防及遏制行动以控制感染传播，包括采取措施保障医护专业人员及感染COVID-19风险增加的患者的安全。粪便微生物群移植（FMT）在治疗艰难梭菌感染中具有公认的作用。在大流行期间，FMT中心和粪便库必须采用一个工作流程，继续确保患者可靠地获得FMT，同时保持程序的安全性和质量。在这份立场文件中，基于现有的最佳证据，全球FMT专家就COVID-19对FMT的影响相关问题提供指导，包括患者选择、供体招募和选择、粪便制造、FMT程序、患者随访和研究活动。
The COVID-19 pandemic has led to an exponential increase in SARS-CoV-2 infections and associated deaths, and represents a significant challenge to healthcare professionals and facilities. Individual countries have taken several prevention and containment actions to control the spread of infection, including measures to guarantee safety of both healthcare professionals and patients who are at increased risk of infection from COVID-19. Faecal microbiota transplantation (FMT) has a well-established role in the treatment of Clostridioides difficile infection. In the time of the pandemic, FMT centres and stool banks are required to adopt a workflow that continues to ensure reliable patient access to FMT while maintaining safety and quality of procedures. In this position paper, based on the best available evidence, worldwide FMT experts provide guidance on issues relating to the impact of COVID-19 on FMT, including patient selection, donor recruitment and selection, stool manufacturing, FMT procedures, patient follow-up and research activities.