The Fungal Biome of the Oral Cavity

The Fungal Biome of the Oral Cavity
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DOI:
10.1007/978-1-4939-3052-4_9
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发表时间:
2016-01-01
期刊:
CANDIDA SPECIES: METHODS AND PROTOCOLS
影响因子:
--
通讯作者:
Ghannoum, Mahmoud
Ghannoum, Mahmoud
中科院分区:
其他
文献类型:
--
作者:
Chandra, Jyotsna;Retuerto, Mauricio;Ghannoum, Mahmoud

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Organisms residing in the oral cavity (oral microbiota) contribute to health and disease, and influence diseases like gingivitis, periodontitis, and oral candidiasis (the most common oral complication of HIV-infection). These organisms are also associated with cancer and other systemic diseases including upper respiratory infections. There is limited knowledge regarding how oral microbes interact together and influence the host immune system. Characterizing the oral microbial community (oral microbiota) in health and disease represents a critical step in gaining insight into various members of this community. While most of the studies characterizing oral microbiota have focused on bacterial community, there are few encouraging studies characterizing the oral mycobiome (the fungal component of the oral microbiota). Our group recently characterized the oral mycobiome in health and disease focusing on HIV. In this chapter we will describe the methods used by our group for characterization of the oral mycobiome.