The Role of Social Media in Recruiting for Clinical Trials in Pregnancy
The Role of Social Media in Recruiting for Clinical Trials in Pregnancy
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DOI：
10.1371/journal.pone.0092744
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发表时间：
2014-03-26
期刊：
影响因子：
3.7
通讯作者：
Koren, Gideon
中科院分区：
文献类型：
--
作者：
Shere, Mahvash;Zhao, Xiu Yan;Koren, Gideon
背景：通过医疗机构使用传统广告招募受孕期妇女参加临床研究是困难和缓慢的。鉴于互联网作为医学信息和研究来源的广泛使用，我们分析了社交媒体在正在进行的孕妇随机开放标签临床试验第二阶段的影响。本研究旨在通过比较两个不同阶段的招聘方法，评估社交媒体作为招聘工具的有效性。方法：研究第一阶段的招聘完全由传统的医疗保健来源组成。这与研究的第二阶段相比，在第二阶段，传统的招聘继续并扩大，而社交媒体被用作补充来源。使用Mann Whitney U检验比较两个阶段的年度招聘率和招聘率。结果：在研究的第一阶段，使用传统来源招聘超过56个月后，有35名女性参与研究，平均招募人数为+/-0.62人/月。在通过社交媒体实施招聘的6个月中，招聘了45名妇女，招聘人数增加了12倍，达到每月+/-7.5人。流失率保持不变，表明社交媒体对招聘产生了积极影响。中断的时间序列分析发现，社交媒体干预后的招聘有显著差异(p
Background: Recruitment of women in the periconceptional period to clinical studies using traditional advertising through medical establishments is difficult and slow. Given the widespread use of the internet as a source for medical information and research, we analyze the impact of social media in the second phase of an ongoing randomized, open-label clinical trial among pregnant women. This study aims to assess the effectiveness of social media as a recruitment tool through the comparison of diverse recruitment techniques in two different phases of the trial.Methods: Recruitment in Phase 1 of the study consisted solely of traditional healthcare-based sources. This was compared to Phase 2 of the study where traditional recruitment was continued and expanded, while social media was used as a supplementary source. Yearly recruitment and recruitment rates in the two phases were compared using the Mann Whitney U test. The contributions of each recruitment source to overall recruitment were analyzed, and the impact of potential confounders on recruitment rate was evaluated using a multiple regression and Interrupted Time Series Analysis.Results: In the first phase of the study, with over 56 months of recruitment using traditional sources, 35 women were enrolled in the study, resulting in a mean rate of +/- 0.62 recruits/month. In the 6 months implementing recruitment through social media, 45 women were recruited, for a 12-fold higher rate of +/- 7.5 recruits/month. Attrition rates remained constant, suggesting that social media had a positive impact on recruitment. The Interrupted Time Series Analysis detected a significant difference in recruitment after the intervention of social media (p