ENDOGENOUS ULTRADIAN RHYTHMS IN RATS EXPOSED TO PROLONGED CONTINUOUS LIGHT
ENDOGENOUS ULTRADIAN RHYTHMS IN RATS EXPOSED TO PROLONGED CONTINUOUS LIGHT
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DOI：
10.1152/ajpregu.1978.235.5.r250
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发表时间：
1978-01-01
影响因子：
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通讯作者：
HIROSHIGE, T
中科院分区：
文献类型：
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作者：
HONMA, KI;HIROSHIGE, T
在暴露于200 lx连续光照3个月以上的个体大鼠中，同时测定了运动活动、体温和血浆皮质酮的昼夜节律。自发活动的自由运行昼夜节律持续约2个月。在持续的光照下，然后节奏逐渐分解。3个月后。暴露后，昼夜节律消失，持续1-2小时的活动爆发在24小时内多次出现。体温也表现出几个突发的波动，这些突发密切相关的时间序列与自发活动。最小二乘谱分析表明，爆发有规律的4-6小时的周期。血浆皮质酮，通过连续采样，在2小时的时间间隔从个别大鼠，也表现出几个分泌事件在一天内。这些间歇性分泌物与自发活动的爆发同步。在长时间连续光照下表现出来的超日成分可能是昼夜节律的基本单位，而超日节律的振荡器是3种功能检查的共同点。
Circadian rhythms of locomotor activity, body temperature and plasma corticosterone were determined simultaneously in individual rats that were exposed to 200 lx continuous light for over 3 mo. Free-running circadian rhythms of locomotor activity persisted for about 2 mo. under continuous light and then the rhythms gradually decomposed. After 3 mo. of exposure, circadian rhythms disappeared and activity bursts of 1-2 h duration manifested themselves several times during a 24 h period. Body temperature also exhibited several bursts of fluctuation and these bursts were closely correlated in their temporal sequence with those of locomotor activity. A least-squares spectrum analysis revealed that the burst had regular 4-6 h periods. Plasma corticosterone, determined by serial sampling at 2 h intervals from individual rats, also exhibited several secretion episodes in a day. These episodic secretions synchronized with bursts of locomotor activity. The ultradian component, manifested under prolonged continuous light, is probably a fundamental unit of the circadian rhythm and an oscillator for the ultradian rhythm is common to the 3 functions examined.