MONOCLONAL-ANTIBODIES AGAINST TROPHECTODERM-SPECIFIC MARKERS DURING MOUSE BLASTOCYST FORMATION
MONOCLONAL-ANTIBODIES AGAINST TROPHECTODERM-SPECIFIC MARKERS DURING MOUSE BLASTOCYST FORMATION
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DOI：
10.1073/pnas.77.7.4113
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发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
JACOB, F
中科院分区：
文献类型：
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作者：
BRULET, P;BABINET, C;JACOB, F
二维凝胶电泳检测小鼠囊胚内细胞团和滋养外胚层的蛋白质特征。某些蛋白质特征滋养外胚层共纯化中间丝滋养外胚层和滋养母细胞瘤细胞系。针对这些中间丝蛋白制备的单克隆抗体标记滋养外胚层中的丝网络，但不在内细胞团细胞中。
Two-dimensional gel electrophoresis allowed the detection of proteins characteristic of inner cell mass and trophectoderm in mouse blastocyst. Certain of the proteins characterizing trophectoderm copurify with intermediate filaments from trophectoderm and a trophoblastoma cell line. A monoclonal antibody prepared against proteins of these intermediate filaments labels a filament network in trophectoderm but not in inner cell mass cells.