Vitamin D: a negative acute phase reactant
Vitamin D: a negative acute phase reactant
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DOI：
10.1136/jclinpath-2012-201301
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发表时间：
2013-07-01
影响因子：
3.4
通讯作者：
Gama, Rousseau
中科院分区：
文献类型：
--
作者：
Waldron, Jenna Louise;Ashby, Helen L.;Gama, Rousseau
目的探讨骨科手术引起的全身炎症反应（SIR）对血清维生素D [25-（OH）D]的影响。方法测定30例膝关节或髋关节置换术患者术前及术后48 h血清25-（OH）D、血清维生素D结合蛋白（VDBP）及尿VDBP。结果术后CRP平均值（SD）升高[5.0（5.5）vs 116.0（81.2）mg/L; P
Objective We evaluated the effect of the systemic inflammatory response (SIR), as provoked by elective orthopaedic surgery, on serum vitamin D [25-(OH) D].Methods Serum 25-(OH) D, serum vitamin D binding protein (VDBP) and urinary VDBP were measured in 30 patients before and 48-hours after knee or hip arthroplasty. C-reactive protein (CRP) was measured to assess the SIR.Results The mean (SD) CRP increased following surgery [5.0 (5.5) vs 116.0 (81.2) mg/L; P