Magnetoelectric backscatter communication for millimeter-sized wireless biomedical implants
Magnetoelectric backscatter communication for millimeter-sized wireless biomedical implants
复制标题
DOI：
10.1145/3495243.3560541
复制
发表时间：
2022-10
期刊：
影响因子：
--
通讯作者：
Zhanghao Yu;Fatima T. Alrashdan;Wei Wang;M. Parker;Xinyu Chen;Frank Y. Chen;Joshua Woods;Zhiyu Chen;Jacob T. Robinson;Kaiyuan Yang
中科院分区：
文献类型：
--
作者：
Zhanghao Yu;Fatima T. Alrashdan;Wei Wang;M. Parker;Xinyu Chen;Frank Y. Chen;Joshua Woods;Zhiyu Chen;Jacob T. Robinson;Kaiyuan Yang
本文介绍了一种无线生物医学植入平台的设计，实施和实验评估，利用磁电效应的无线供电和双向通信。作为一种新兴的无线功率传输方法，磁电技术有望用于mm级生物植入物，因为与其他模式相比，磁电技术具有上级错位灵敏度、高效率和低组织吸收[46，59，60]。利用相同的物理机制进行功率和通信对于植入物小型化是至关重要的，但低功率磁电上行链路通信尚未实现。首次利用匡威磁致伸缩效应设计并演示了毫米级植入物的近零功率磁电背散射。演示系统由8.2 mm 3无线植入式器械和定制便携式收发器组成。植入物的ASIC与磁电换能器接口，通过改变换能器的负载对上行链路数据进行编码，从而导致频移键控调制的谐振频率变化。磁电反向散射信号由外部收发器通过频率到数字转换来感测和解调。通过对数据调制和恢复的设计优化，该系统在335 kHz载波频率下实现了> 1 kbps的数据速率，通信距离大于2 cm，误码率小于1 E-3。此外，我们还验证了拟议的无线刺激和传感系统，并通过1.5厘米的猪组织进行了离体测试。所提出的磁电反向散射方法提供了一条通往小型化无线生物植入物的道路，用于先进的生物医学应用，如闭环神经调节。
This paper presents the design, implementation, and experimental evaluation of a wireless biomedical implant platform exploiting the magnetoelectric effect for wireless power and bi-directional communication. As an emerging wireless power transfer method, magnetoelectric is promising for mm-scaled bio-implants because of its superior misalignment sensitivity, high efficiency, and low tissue absorption compared to other modalities [46, 59, 60]. Utilizing the same physical mechanism for power and communication is critical for implant miniaturization, but low-power magnetoelectric uplink communication has not been achieved yet. For the first time, we design and demonstrate near-zero power magnetoelectric backscatter from the mm-sized implants by exploiting the converse magnetostriction effects. The system for demonstration consists of an 8.2-mm3 wireless implantable device and a custom portable transceiver. The implant's ASIC interfacing with the magnetoelectric transducer encodes uplink data by changing the transducer's load, resulting in resonance frequency changes for frequency-shift-keying modulation. The magnetoelectrically backscattered signal is sensed and demodulated through frequency-to-digital conversion by the external transceiver. With design optimizations in data modulation and recovery, the proposed system archives > 1-kbps data rate at the 335-kHz carrier frequency, with a communication distance greater than 2 cm and a bit error rate less than 1E-3. Further, we validate the proposed system for wireless stimulation and sensing, and conducted ex-vivo tests through a 1.5-cm porcine tissue. The proposed magnetoelectric backscatter approach provides a path towards miniaturized wireless bio-implants for advanced biomedical applications like closed-loop neuromodulation.