Mixed cryoglobulinemia-associated membranoproliferative glornerulonephritis, disclosing gastric MALT lymphoma

Mixed cryoglobulinemia-associated membranoproliferative glornerulonephritis, disclosing gastric MALT lymphoma
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DOI:
10.1016/s0242-6498(06)70719-2
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发表时间:
2006-09-01
影响因子:
0.5
通讯作者:
Copin, Marie-Christine
Copin, Marie-Christine
中科院分区:
医学4区
文献类型:
--
作者:
Buob, David;Copin, Marie-Christine

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我们报告一例混合冷球蛋白相关膜增殖性肾小球肾炎,揭示MAL t型胃淋巴瘤。在报告的病例中,肾小球肾炎与II型混合冷球蛋白血症相关的关节和皮肤症状相关。MALT淋巴瘤的诊断模式为胃活检。肾脏病理检查显示相对少见的发现,即中膜增生性肾小球肾炎锁定通常腔内血栓。虽然典型,肾脏恶性淋巴瘤的表现是罕见的,很少允许淋巴瘤诊断。在适当的治疗下,随着淋巴瘤的消退,肾脏生物学功能得到改善。本病例强调了胃镜检查在低温毒血症病因学研究中的益处。
We report a case of a mixed cryoglobulinemio-associated membranoproliferative glomerulonephritis, disclosing gastric lymphoma of MAL T-type. In the reported case, glomerulonephritis was associated with joint and skin symptoms related to type II mixed cryoglobulinemia. MALT lymphoma diagnosis was mode by gastric biopsy. Renal pathological examination showed relatively uncommon findings, ie mesongioproliferative glomerulonephritis locking usual intraluminal thrombi. Although classical, renal manifestations of malignant lymphomas are uncommon, and rarely allow lymphoma diagnosis. The renal biological function improves as the lymphoma regresses with appropriated treatment. This case underlines the benefit of gastroscopy in cryoglo-bulinemic etiological research.