Critical peak resolution in multicomponent chromatograms
Critical peak resolution in multicomponent chromatograms
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DOI：
10.1021/ac970241y
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发表时间：
1997-08-01
影响因子：
7.4
通讯作者：
Felinger, A
中科院分区：
文献类型：
--
作者：
Felinger, A
确定了多组分色谱峰重叠的临界度。由于相邻峰的高度差异很大，在多组分分离中不能使用单一的临界峰分辨率；必须考虑峰高分布来确定临界峰分辨率的分布。导出了临界峰分辨率的解析表达式，由此可以通过积分得到平均或最大可能峰分辨率，该理论模型可以很容易地应用于任何峰高分布。
The critical degree of peak overlap is determined for multicomponent chromatograms. As the heights of adjacent peaks significantly differ, no single value of critical peak resolution can be used in multicomponent separations; one has to determine the distribution of the critical peak resolutions, taking into account the peak height distribution. An analytical expression is derived for the critical peak resolution, from which one can obtain the average or maximum probable peak resolution by integration, The theoretical model can be applied to any peak height distribution with ease.