Frequency of fetal anomalies in sonographically detected polyhydramnios

Frequency of fetal anomalies in sonographically detected polyhydramnios
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超声检测羊水过多胎儿异常的频率

DOI:
10.7863/jum.1993.12.1.11
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发表时间:
1993
影响因子:
2.3
通讯作者:
Mitchell S. Colbus
Mitchell S. Colbus
中科院分区:
医学4区
文献类型:
--
作者:
N. Damato;R. A. Filly;Ruth B. Goldstein;P. Callen;James D. Goldberg;Mitchell S. Colbus

文献摘要

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105例符合羊水袋深度大于8 cm的患者为羊水过多。在这些病例中,82%是单胎怀孕,18%是双胞胎怀孕。羊水过多的程度与检测到异常的概率直接相关。对于最低级别(口袋深度8到9.5厘米)的胎儿,50%的胎儿表现出异常,而最高级别(16.0厘米或更深)的胎儿出现异常的风险为88%。总体而言,63%的羊水过多孕妇表现出异常。超声检查发现所有这些都是异常的。有三次对潜在异常的错误诊断。双胞胎的单绒毛膜异常(双胞胎输血综合征和无心双胞胎)和单胎中的胃肠道异常是最常见的异常。然而,在研究组中出现了广泛的异常。在我们的研究队列中,只有五位糖尿病母亲,她们中的每一位都因相关的胎儿畸形而进一步合并妊娠。
One hundred and five patients who met the criterion of having an amniotic fluid pocket depth greater than 8.0 cm were categorized as polyhydramniotic. Of these cases, 82% were singleton pregnancies and 18% were twin pregnancies. The degree of polyhydramnios correlated directly with the probability that an anomaly would be detected. For the lowest rank group (pocket depth of 8 to 9.5 cm), 50% of fetuses manifested an anomaly, whereas the highest rank (16.0 cm or greater pocket depth) carried an 88% risk for an anomaly. Overall, 63% of pregnancies with polyhydramnios revealed anomalies. Sonography found all to be anomalous. There were three false diagnoses of potential anomalies. Monochorionic anomalies of twinning (twin transfusion syndrome and acardiac twin) and gastrointestinal anomalies among singletons were the most commonly seen abnormalities. However, a broad spectrum of anomalies was represented in the study group. Only five diabetic mothers were seen in our study cohort, and in each of them the pregnancy was further complicated by an associated fetal anomaly.