Differing intergenerational birth weights among the descendants of US-born and foreign-born whites and African Americans in Illinois
Differing intergenerational birth weights among the descendants of US-born and foreign-born whites and African Americans in Illinois
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DOI：
10.1093/aje/155.3.210
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发表时间：
2002-02-01
影响因子：
5
通讯作者：
David, RJ
中科院分区：
文献类型：
--
作者：
Collins, JW;Wu, SY;David, RJ
作者分析了伊利诺伊州的生命记录，以确定美国出生和外国出生的白色和非洲裔美国妇女后代的代际出生体重模式。在第一代美国出生的白色女性的后代中，（n = 91，061），第3代雌性的出生体重比其第2代母亲的出生体重高65 g（p <0.0001）;第3代婴儿中度低出生体重降低10%（1，500 - 2，499 g）的发生率分别为5.0%和5.5%（相对风险= 0.9，95%置信区间：0.9，0.9）。在第1代欧洲出生的白色女性的后代（n = 3，339）中，第3代女性的出生体重比其第2代母亲的出生体重高45 g（p <0.0001）。在第一代美国出生的非洲裔美国妇女的后代（n = 31，699）中，第三代女性的出生体重比第二代母亲的出生体重高17 g（p <0.001）。在第一代非洲/加勒比出生妇女的后代（n = 104）中，第三代女性的出生体重比第二代母亲的出生体重轻57克;第三代女性的中度低出生体重率比第二代母亲高40%：9.6%比6.7%。（相对危险度= 1.4，95%置信区间：0.6，3.6）。母亲的年龄和婚姻状况不能解释出生体重的趋势。作者得出结论，预期的出生体重代际上升不会发生在外国出生的非洲裔美国妇女的直系女性后代中。
The authors analyzed Illinois vital records to determine the intergenerational birth weight patterns among the descendants of US-born and foreign-born White and African-American women. Among the descendants of the generation 1 US-born White women (n = 91,061), generation 3 females had a birth weight 65 g more than that of their generation 2 mothers (p < 0.0001); generation 3 infants had a 10% lower moderately low birth weight (1,500-2,499 g) rate than did their generation 2 mothers: 5.0% versus 5.5% percent, respectively (relative risk = 0.9, 95% confidence interval: 0.9, 0.9). Among the descendants of generation 1 European-born White women (n = 3,339), generation 3 females had a birth weight 45 g more than that of their generation 2 mothers (p < 0.0001). Among the descendants of generation 1 US-born African-American women (n = 31,699), generation 3 females had a birth weight 17 g more than that of their generation 2 mothers (p < 0.001). Among the descendants of generation 1 African/Caribbean-born women (n = 104), generation 3 females had a birth weight 57 g less than that of their generation 2 mothers; generation 3 females had a 40% greater moderately low birth weight rate than did their generation 2 mothers: 9.6% percent versus 6.7% percent (relative risk = 1.4, 95% confidence interval: 0.6, 3.6). Maternal age and marital status did not account for the birth weight trends. The authors conclude that the expected intergenerational rise in birth weight does not occur among the direct female descendants of foreign-born African-American women.