Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?
Predictors of selective laser trabeculoplasty success in open angle glaucoma or ocular hypertension: does baseline tonography have a predictive role?
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DOI：
10.1136/bjophthalmol-2019-315489
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发表时间：
2020-10-01
影响因子：
4.1
通讯作者：
Lim, Kin Sheng
中科院分区：
文献类型：
--
作者：
Alaghband, Pouya;Galvis, Elizabeth Angela;Lim, Kin Sheng
背景选择性激光小梁成形术（SLT）成功治疗初治开角型青光眼（OAG）和高眼压（OHT）患者的决定因素尚未完全了解。因此，我们进行了这项研究，以探索成功的预测因素。方法：本研究是对英国伦敦圣托马斯医院接受原发性SLT患者的既往数据库进行回顾性分析。OAG和OHT患者接受了初级360度SLT治疗，并有可靠的基线TOF，随访至少1年。进行单因素和多因素分析以找到成功的决定因素。结果2006年8月至2010年2月间，174例患者接受了初级360度SLT治疗，并进行了基线TOF测量。其中，72名受试者符合资格标准。在多变量回归分析中，与成功相关的唯一变量是基线眼压（IOP） (R-2=0.32, β =-0.51, p
Background The determinants of success of selective laser trabeculoplasty (SLT) in treatment-naive patients with open angle glaucoma (OAG) and ocular hypertension (OHT) have not been understood fully. Therefore, we have conducted this study to explore the predictors of success.Methods This is a retrospective review of a pre-existing database of patients who had received primary SLT at St Thomas' Hospital, London, UK. Patients with OAG and OHT who had received primary 360 degrees SLT treatment and had reliable baseline tonographic outflow facility (TOF) with minimum of 1 year of follow-up were included. Univariate and multivariate analyses were performed to find the determinants of success.Results One hundred and seventy-four patients between August 2006 and February 2010 had received primary 360 degrees SLT treatment and had baseline TOF measurement. Of these, 72 subjects fulfilled the eligibility criteria. In multivariate regression analysis, the only variable associated with success was baseline intraocular pressure (IOP) (R-2=0.32, beta=-0.51, p