PHEROMONE-INDUCED 2ND-MESSENGER SIGNALING IN INSECT ANTENNAE
PHEROMONE-INDUCED 2ND-MESSENGER SIGNALING IN INSECT ANTENNAE
复制标题
DOI：
10.1016/0965-1748(93)90063-x
复制
发表时间：
1993-10-01
影响因子：
3.8
通讯作者：
BREER, H
中科院分区：
文献类型：
--
作者：
BOEKHOFF, I;SEIFERT, E;BREER, H
来自Heliothis virescens的触角制剂在亚秒时间范围内响应性信息素成分与快速瞬时肌醇三磷酸信号的混合，这被认为是化学-电转导过程的主要反应。信息素诱导的第二信使反应是物种和性别特异性的。混合物的主要成分（z -11-十六烯醛）比次要成分（z -9-十四烯醛）更有效。应用高剂量的信息素引起延迟和持续的增加环GMP。cGMP水平的升高显著降低了信息素诱导的ip3反应，表明两种第二信使通路之间存在相当大的交叉对话，表明cGMP可能参与了触角受体细胞的适应。
Antennal preparations from Heliothis virescens respond to a blend of sex-pheromone components with a rapid and transient inositol trisphosphate signal in the subsecond time range that is supposed to be the primary reaction of the chemo-electrical transduction process. The pheromone-induced second messenger response is species- and sex-specific. The major component of the blend (Z-11-hexadecenal) is much more potent than one of the minor components (Z-9-tetradecenal). Application of high pheromone doses elicited a delayed and sustained increase of cyclic GMP. Elevated cGMP-levels significantly reduced the pheromone-induced IP3-response, indicating a considerable cross-talk between both second messenger pathways and suggesting that cGMP may be involved in adaptation of antennal receptor cells.