Dielectric Characterization of PCL-Based Thermoplastic Materials for Microwave Diagnostic and Therapeutic Applications
Dielectric Characterization of PCL-Based Thermoplastic Materials for Microwave Diagnostic and Therapeutic Applications
复制标题
DOI：
10.1109/tbme.2011.2157918
复制
发表时间：
2012-03-01
影响因子：
4.6
通讯作者：
Hagness, Susan C.
中科院分区：
文献类型：
--
作者：
Aguilar, Suzette M.;Shea, Jacob D.;Hagness, Susan C.
我们建议使用聚己内酯（PCL）为基础的热塑性网格作为微波成像和微波热疗治疗的组织固定界面。研究了两种PCL基热塑性材料在0.5-3.5 GHz频率范围内的介电性能。的频率依赖性的介电常数和有效的导电率的PCL基热塑性塑料的特征在于使用测量的微带传输线制造的基板上的热塑性网格组成。我们还研究了基于PCL的热塑性补片对微波乳腺成像的影响。我们使用一个数值试验床，包括以前报道的3-D解剖学上逼真的乳房幻影和多频微波逆散射算法。我们证明了PCL基热塑性材料和假定的植物油生物相容性介质充分匹配，使得PCL层可以被成像溶液忽略而不牺牲成像质量。我们的研究结果表明，PCL为基础的热塑性塑料是有前途的材料作为组织固定结构的微波诊断和治疗应用。
We propose the use of a polycaprolactone (PCL)-based thermoplastic mesh as a tissue-immobilization interface for microwave imaging and microwave hyperthermia treatment. An investigation of the dielectric properties of two PCL-based thermoplastic materials in the frequency range of 0.5-3.5 GHz is presented. The frequency-dependent dielectric constant and effective conductivity of the PCL-based thermoplastics are characterized using measurements of microstrip transmission lines fabricated on substrates comprised of the thermoplastic meshes. We also examine the impact of the presence of a PCL-based thermoplastic mesh on microwave breast imaging. We use a numerical test bed comprised of a previously reported 3-D anatomically realistic breast phantom and a multi-frequency microwave inverse scattering algorithm. We demonstrate that the PCL-based thermoplastic material and the assumed biocompatible medium of vegetable oil are sufficiently well matched such that the PCL layer may be neglected by the imaging solution without sacrificing imaging quality. Our results suggest that PCL-based thermoplastics are promising materials as tissue immobilization structures for microwave diagnostic and therapeutic applications.