Circulating heat shock proteins and inflammatory markers in patients with idiopathic left ventricular dysfunction: their relationships with myocardial and microvascular impairment

Circulating heat shock proteins and inflammatory markers in patients with idiopathic left ventricular dysfunction: their relationships with myocardial and microvascular impairment
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DOI:
10.1379/csc-272.1
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发表时间:
2007-09-01
影响因子:
3.8
通讯作者:
Neglia, Danilo
Neglia, Danilo
中科院分区:
生物学3区
文献类型:
--
作者:
Giannessi, Daniela;Colotti, Chiara;Neglia, Danilo

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关于非动脉粥样硬化性心脏病引起的左心室功能障碍患者外周血Hsp72、Hsp60和抗Hsp60抗体水平的信息很少。本研究检测了44例健康对照和82例冠状动脉造影正常患者的血清Hsp72、Hsp60和抗Hsp60抗体、IL-6和c反应蛋白(CRP)(左室射血分数[EF] >= 50%, n = 22; >= 35% ~ < 50%, n = 32;
Little information is available on peripheral levels of Hsp72, Hsp60, and anti-Hsp60 antibodies in patients with left ventricular (LV) dysfunction due to non-atherosclerotic cardiac disease. In this study, serum Hsp72, Hsp60 and anti-Hsp60 antibodies, IL-6, and C-reactive protein (CRP) were measured in 44 healthy controls and in 82 patients with angiographically normal coronary arteries (LV ejection fraction [EF] >= 50%, n = 22; >= 35% to < 50%, n = 32;