NATURAL HISTORY AND PRINCIPLES OF TREATMENT OF PRIMARY ANGLE-CLOSURE GLAUCOMA
NATURAL HISTORY AND PRINCIPLES OF TREATMENT OF PRIMARY ANGLE-CLOSURE GLAUCOMA
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DOI：
10.1016/0002-9394(66)91200-1
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发表时间：
1966-01-01
影响因子：
4.2
通讯作者：
LOWE, RF
中科院分区：
文献类型：
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作者：
LOWE, RF
644罗纳德·F·洛间歇性闭角型青光眼是其最典型的特征，建议使用“间歇性闭角型青光眼”一词，以避免与其他类型的青光眼混淆。间歇性闭角型青光眼是指发作之间功能正常的眼睛由于闭角型青光眼反复发作而引起的眼压升高。角度闭合可以是部分的，也可以是完全的，取决于相对的瞳孔阻塞，而相对的瞳孔阻塞又遵循更一般的身体变化或特定的眼睛活动。触发机制仍不清楚。间歇性房角闭合在20岁以前是非常罕见的。由于晶状体的持续生长，随着年龄的增长，前房变得越来越浅14，这可能是决定以后生活中房角关闭频率增加的一个因素。大多数间歇性闭角型青光眼发作的开始年龄在55岁到60岁之间，13岁，尽管晶状体在一生中不断增长。对于一些患者，症状可能要到80岁以上才会出现。主要症状是一只眼或一只眼以上疼痛，视力模糊，晕轮，恶心或呕吐。这些症状的强度因患者不同而不同，但往往是个体特有的。12攻击往往发生在可识别的诱发因素之后，这些因素也是个人特有的特征。13名患者经常识别发作前的活动，通过避免这种活动，他们的症状严重程度或频率降低。每一集都是短时间的，并自发地重新开始。发作不可避免地会因睡眠而终止，因此，如果症状持续到第二天，就会出现并发症，或者症状来自不同的疾病(如偏头痛)。间歇性闭角型青光眼通常是良性的，但每一次发作都是一个危险信号，指向一个破坏性的急性角度。
644 RONALD F. LOWE intermittence of angle closure is their most characteristic feature, the term" intermittent angle-closure glaucoma" is recommended to avoid confusion with other forms. Intermit tent angle-closure glaucoma is here defined as repeated episodes of raised intraocular pressure caused by angle closure in eyes that function normally between the attacks. The angle closure may be partial or com plete and is dependent upon a relative pupil block which, in turn, follows more general body changes or particular ocular activities. The trigger mechanism remains unknown. Intermittent angle closure is very rare be fore the age of 20 years. Because of con tinued growth of the lens, the anterior chamber becomes increasingly shallow as age advances14 and this may be a factor in determining the increased frequency of angle closure later in life. The age at which most intermittent angle-closure glaucoma attacks begin is between 55 and 60 years, 13 although the lens continues to grow throughout life. With some patients, symp toms may not occur until past the age of 80 years.The cardinal symptoms are aching in or above one eye, blurred vision, haloes, nausea or vomiting. The intensity of each of these symptoms varies from patient to patient but tends to be characteristic for the in dividual. 12 The attacks tend to occur fol lowing recognizable precipitating factors which are also peculiarly characteristic for the individual. 13 Patients frequently recog nize the activity that precedes their attacks and, by avoiding this activity, their symp toms are reduced in severity or frequency. Each episode is of short duration and re lieved spontaneously. The attacks are invari ably terminated by sleep so that if symptoms persist into the second day a complication is present or the symptoms are from a differ ent disease (such as migraine). Intermittent angle-closure glaucoma is typically benign but each episode is a danger signal pointing to a destructive acute angle-