Volumetric tumor measurement using three-dimensional ultrasound:: In vitro phantom study on measurement accuracy under various scanning conditions

Volumetric tumor measurement using three-dimensional ultrasound:: In vitro phantom study on measurement accuracy under various scanning conditions
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DOI:
10.1016/j.ultrasmedbio.2003.09.010
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发表时间:
2004-01-01
影响因子:
2.9
通讯作者:
Han, H
Han, H
中科院分区:
医学3区
文献类型:
--
作者:
Park, SH;Choi, BI;Han, H

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研究了影响三维超声(US)测量肿瘤体积的因素。使用配备4- 8 MHz弯曲阵列和5- 10 MHz线性阵列机械容积换能器的3-D US装置,以及由20个火腿片(8.6类似于10.5 mL)嵌入模拟高回声肿瘤的琼脂凝胶制成的US体模。肿瘤体积测量受超声焦点位置和肿瘤深度的显著影响。当病灶位于探头下方2 cm和8 cm时,5 cm深的肿瘤分别比病灶位于探头下方5 cm时大5.6% ± 2.8%(平均值± SD)和8.3% ± 2.2%(与肿瘤位置相同)(p <0.05)。
Factors influencing volumetric tumor measurement using 3-D ultrasound (US) were investigated. A 3-D US unit equipped with 4- to 8-MHz curved-array and 5- to 10-MHz linear-array mechanical volume transducers, and a US phantom made of 20 ham pieces (8.6 similar to 10.5 mL) embedded in agar gel that simulated hyperechoic tumors, were used. Volumetric tumor measurement was significantly affected by the position of US focus and tumor depth. When focus was at 2 cm and 8 cm below the transducer, 5-cm-deep tumors were measured 5.6%+/-2.8% (mean+/-SD) and 8.3%+/-2.2% bigger, respectively, than when focus was at 5 cm below the transducer, the same position as tumors (p