Minimum graft volume for successful adult-to-adult living donor liver transplantation for fulminant hepatic failure.

Minimum graft volume for successful adult-to-adult living donor liver transplantation for fulminant hepatic failure.
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成功进行成人对成人活体肝移植治疗暴发性肝衰竭的最小移植体积。

DOI:
10.1097/00007890-199609150-00029
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发表时间:
1996
期刊:
影响因子:
6.2
通讯作者:
Ching‐lung Lai
Ching‐lung Lai
中科院分区:
医学2区
文献类型:
--
作者:
C. Lo;S. Fan;J. Chan;W. Wei;Ronald J.W. Lo;Ching‐lung Lai

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成人间活体肝移植的主要局限性是从供体安全获取的移植物的大小是否足够。本报告描述了一个22岁的女性4期肝昏迷由于暴发性肝功能衰竭谁是成功地治疗使用小的左叶移植从她的父亲。移植物重量为受体体重的0.6%,或理想肝脏重量的25%。避免热缺血、缩短冷缺血时间和早期治疗排斥反应是优化小体积移植物功能的重要因素。由于左叶占成人肝脏总体积的23-36%,因此在大多数情况下,可以从与受体大小相似的供体中获得足够大小的左叶移植物。
The major limitation of adult-to-adult living donor liver transplantation is the adequacy of the size of the graft that can be safely harvested from the donor. The present report describes a 22-year-old woman with stage 4 hepatic coma due to fulminant hepatic failure who was successfully treated using a small-for-size left lobe graft from her father. The graft weight was 0.6% of the recipient's body weight, or 25% of her ideal liver weight. Avoidance of warm ischemia, short cold ischemic time, and early treatment of rejection are important elements in optimizing small-for-size graft function. Since the left lobe represents 23-36% of the total liver volume of an adult, it is possible, in most cases, to harvest a left lobe graft of adequate size from a donor of similar size as the recipient.
Hidetoshi MATSUNAMI:“暴发性肝衰竭的与生活相关的肝移植。”
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DOI: 10.1097/00000658-199301000-00014
发表时间: 1993-01-01
期刊: ANNALS OF SURGERY
影响因子: 9
作者:
TANAKA, K;UEMOTO, S;OZAWA, K
通讯作者: OZAWA, K