ISOLATION OF MEASLES VIRUS AT AUTOPSY IN CASES OF GIANT-CELL PNEUMONIA WITHOUT RASH
ISOLATION OF MEASLES VIRUS AT AUTOPSY IN CASES OF GIANT-CELL PNEUMONIA WITHOUT RASH
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DOI：
10.1056/nejm195910292611801
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发表时间：
1959-01-01
影响因子：
158.5
通讯作者：
CHEATHAM, WJ
中科院分区：
文献类型：
--
作者：
ENDERS, JF;MCCARTHY, K;CHEATHAM, WJ
巨细胞肺炎，通常被称为赫克特巨细胞肺炎，是一种间质性肺炎，迄今为止只在儿童中观察到。其特征是存在多核巨细胞，伴核内和胞浆内包涵体。123456789其他病理学特征是浸润中单核细胞占优势，支气管和细支气管上皮鳞状化生，肺泡衬里细胞增殖，以及肺以外器官中偶尔出现巨细胞。图1、2和3显示了受累肺的特征性变化。巨细胞性肺炎的诊断，一直以来......
GIANT-cell pneumonia, often referred to as Hecht's giant-cell pneumonia, is an interstitial pneumonitis that has so far been observed only in children. It is characterized by the presence of multinuclear giant cells with intranuclear and intracyto-plasmic inclusion bodies.123456789Additional pathological features are a preponderance of mononuclear cells in the infiltrate, squamous metaplasia of the bronchial and bronchiolar epithelium, proliferation of alveolar lining cells and the occurrence in occasional cases of giant cells in organs other than the lungs. The changes characteristically found in the affected lung are illustrated in Figures 1,2and3. The diagnosis of giant-cell pneumonia, which has been . . .