Vesicoureteral reflux and clinical outcomes in infants with prenatally detected hydronephrosis
Vesicoureteral reflux and clinical outcomes in infants with prenatally detected hydronephrosis
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DOI：
10.1097/01.ju.0000026907.65728.6e
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发表时间：
2002-10-01
影响因子：
6.6
通讯作者：
Coplen, DE
中科院分区：
文献类型：
--
作者：
Brophy, MM;Austin, PF;Coplen, DE
目的：探讨膀胱输尿管结石的发生率。材料与方法：我们回顾性分析了1992年至1998年期间来我院评估产前检测到的肾积水的患儿的病历。测量变量包括超声和排尿膀胱尿道造影结果，感染和临床返流outcomes.Results：膀胱输尿管返流被确定在40 234名婴儿（21%），includingConclusions：反流的发病率增加，更大程度的超声扩张，但正常的超声并不排除反流，因此，排尿膀胱尿道造影建议在所有儿童产前检测肾积水。由于尿路感染是罕见的预防，抗生素应继续，直到反流解决和/或肾盂积水显着改善。男性占24%，女性占13%。肾积水程度与反流发生率之间存在显著相关性。尿路感染是不常见的，并确定在7.5%的儿童预防反流和4%的正常排尿膀胱尿道造影。在大多数（58%）病例中，通过药物治疗解决了反流。
Purpose: We evaluate the incidence of vesicoureteral. reflux and urinary tract infections in infants with prenatally detected hydronephrosis.Materials and Methods: We retrospectively reviewed the charts of children referred to our hospital for evaluation of prenatally detected hydronephrosis between 1992 and 1998. Measured variables included ultrasound and voiding cystourethrogram findings, and infectious and clinical reflux outcomes.Results: Vesicoureteral reflux was identified in 40 of 234 infants (21%), includingConclusions: The incidence of reflux increases with greater degrees of sonographic dilatation but a normal ultrasound does not exclude reflux and, therefore, voiding cystourethrogram is recommended in all children with prenatally detected hydronephrosis. Since urinary tract infections are uncommon with prevention, antibiotics should be continued until reflux resolves and/or hydronephrosis significantly improves. 24% of males and 13% of females. A significant correlation was found between the degree of hydronephrosis and incidence of reflux. Urinary tract infections were uncommon and identified in 7.5% of children on prevention for reflux and 4% with normal voiding cystourethrogram. In the majority (58%) of cases reflux resolved with medical management.