Aortic valve sclerosis is an echocardiographic indicator of significant coronary disease in patients undergoing diagnostic coronary angiography
Aortic valve sclerosis is an echocardiographic indicator of significant coronary disease in patients undergoing diagnostic coronary angiography
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DOI：
10.1111/j.1368-5031.2004.00219.x
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发表时间：
2005-01-01
影响因子：
2.6
通讯作者：
Hung, KC
中科院分区：
文献类型：
--
作者：
Hsu, SY;Hsieh, IC;Hung, KC
主动脉瓣硬化（AVS）被认为是累及主动脉瓣的全身性动脉粥样硬化的表现。在一项基于人群的研究中，它与较高的心血管发病率和死亡率相关。本研究应用经胸超声心动图（TTE）评价了357例疑似冠心病（CAD）患者的AVS患病率及其意义。这项工作表明，在这种临床环境中，AVS是显著CAD的独立超声心动图预测因子（O.R. = 3.18; 95%置信区间1.52-6.7; p = 0.002）。其他独立预测因素包括男性、糖尿病和高血糖症。AVS对CAD存在的预测价值在女性和年龄较大的受试者中更为突出。
Aortic valve sclerosis (AVS) is considered to be a manifestation of generalised atherosclerosis that involves the aortic valve. It has been associated with higher cardiovascular morbidity and mortality in a population-based study. This investigation used transthoracic echocardiography (TTE) to evaluate the prevalence and significance of AVS in 357 Chinese patients with suspected coronary artery disease (CAD). This work reveals that AVS is an independent echocardiographic predictor of significant CAD in such clinical setting (O.R. = 3.18; 95% confidence interval 1.52-6.7; p = 0.002). Other independent predictors include male gender, diabetes mellitus and hypertriglyceridemia. The predictive value of AVS for the presence of CAD is more prominent in females and in subjects aged