Plaque Characteristics of Thin-Cap Fibroatheroma Evaluated by OCT and IVUS
Plaque Characteristics of Thin-Cap Fibroatheroma Evaluated by OCT and IVUS
复制标题
DOI：
10.1016/j.jcmg.2011.03.014
复制
发表时间：
2011-06-01
影响因子：
14
通讯作者：
Yoshida, Kiyoshi
中科院分区：
文献类型：
--
作者：
Miyamoto, Yoshinori;Okura, Hiroyuki;Yoshida, Kiyoshi
目的：本研究的目的是通过综合后向散射血管内超声（IB-IVUS）评估光学相干断层扫描（OCT）衍生的薄帽纤维粥样瘤（TCFA）的斑块特征。射频信号衍生的IVUS组织表征技术已成为临床可用的技术，可提供客观定量的冠状动脉壁斑块特征。综合后向散射IVUS是一种可能提供oct衍生TCFA定量斑块特征的组织表征方法。方法选择斑块负荷bbbb40 %的81个冠状动脉病变，用IB-IVUS和oct进行分析。oct衍生的TCFA定义为薄纤维帽（= 55%）的存在，纤维化面积百分比= 1.0是oct衍生的TCFA的预测因子。结论：IB-IVUS评估oct来源的TCFA具有更大的斑块负担和正重构，主要是脂质成分和较少的纤维斑块。[J]中华医学会心脏科杂志2011；4:638-46
OBJECTIVES The purpose of this study was to assess plaque characteristics of optical coherence tomography (OCT)-derived thin-cap fibroatheroma (TCFA) by integrated backscatter intravascular ultrasound (IB-IVUS).BACKGROUND Radiofrequency signal-derived IVUS tissue characterization technology has become clinically available and provided objective and quantitative plaque characteristics of the coronary vessel wall. Integrated backscatter IVUS is one of the tissue characterization methods that can possibly provide quantitative plaque characteristics of the OCT-derived TCFA.METHODS Eighty-one coronary lesions with plaque burden >40% were selected and analyzed with both IB-IVUS and OCT. The OCT-derived TCFA was defined as a presence of thin fibrous cap (= 55%, percentage fibrosis area = 1.0 were predictors of OCT-derived TCFA.CONCLUSIONS The OCT-derived TCFA had larger plaque burden and positive remodeling with predominant lipid component and less fibrous plaque assessed by IB-IVUS. (J Am Coll Cardiol Img 2011;4:638-46) (C) 2011 by the American College of Cardiology Foundation