Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young
Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young
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DOI：
10.1007/s00234-019-02269-y
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发表时间：
2019-11-01
期刊：
影响因子：
2.8
通讯作者：
Kaufmann, Timothy J.
中科院分区：
文献类型：
--
作者：
Johnson, Derek R.;Giannini, Caterina;Kaufmann, Timothy J.
目的 青年多形性低级别神经上皮肿瘤（PLNTY）是一种近期被描述的致癫痫性肿瘤。顾名思义，PLNTY是一种惰性肿瘤，最常见于儿童或青年人群。现有文献中对PLNTY的影像学特征描述并不充分。
方法 我们进行了一项回顾性研究，确定了9例经病理证实为PLNTY且有术前影像学资料的患者，以确定可能有助于对该疾病进行可靠影像学诊断的共同特征。
结果 患者年龄为5 - 34岁（中位年龄16岁），其中7例（78%）为女性。大多数肿瘤具有高度特征性的表现，包括位于颞叶（6/9；67%）、钙化（8/9；89%）、皮质/皮质下起源（8/9；89%）、囊性成分（8/9；89%）以及相对少见的强化（3/9；33%）。
结论 PLNTY表现出特征性的钙化、皮质下位置以及常见的颞叶定位，这些特征可能使放射科医生在适当的临床背景下前瞻性地提出诊断。
Purpose Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are indolent tumors most often encountered in the pediatric or young adult population. The imaging features of PLNTY are not well characterized in the existing literature.Methods We performed a retrospective review, identifying nine patients with pathologically proven PLNTY and available preoperative imaging in order to identify common features which may facilitate confident imaging diagnosis of this entity.Results Patients were ages 5 to 34 years (median 16 years), and seven (78%) were female. Most tumors had a highly characteristic appearance, with temporal lobe location (6/9; 67%), calcification (8/9; 89%), cortical/subcortical origin (8/9; 89%), cystic components (8/9; 89%), and relatively infrequent contrast enhancement (3/9; 33%).Conclusion PLNTYs demonstrate characteristic calcification, subcortical location, and frequent temporal lobe localization, features that may allow radiologists to prospectively suggest the diagnosis in the proper clinical setting.