The structure of the mer operon.
The structure of the mer operon.
复制标题
mer操纵子的结构。
DOI：
10.1007/978-1-4613-2447-8_49
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Wisdom,S
中科院分区：
文献类型：
--
作者：
Barrineau,P;Gilbert,P;Jackson,WJ;Jones,CS;Summers,AO;Wisdom,S
The DNA sequence has been determined for a 3.8-kb region which encodes the mercury-resistance (mer) operon of the IncFII plasmid NRl. The sequence reveals 4 open reading frames which could encode proteins of 12,522, 9,429, 14,965, and 58,912 d corresponding to the 4 previously+described Hg-inducible proteins detected in minicells carrying mer plasmids. The Hg(II) reductase protein sequence is about 90% homologous to that of Tn501, but the DNA sequence shows a homology of 60–70% to that of Tn501 except for short regions of very high homology. The entiremerregion is 63.4% G-C overall. The region encoding themerR(positive regulatory) function has 3 possible open reading frames, 2 of which overlap in one direction and the third of which reads in the opposite direction. Attempts to visualize the polypeptide(s) encoded by themerRcistron were unsuccessful.
