APACHE-II SCORE FOR ASSESSMENT AND MONITORING OF ACUTE PANCREATITIS
APACHE-II SCORE FOR ASSESSMENT AND MONITORING OF ACUTE PANCREATITIS
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DOI：
10.1016/s0140-6736(89)90381-4
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发表时间：
1989-07
期刊：
影响因子：
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通讯作者：
M. Larvin;M. Mcmahon
中科院分区：
文献类型：
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作者：
M. Larvin;M. Mcmahon
将急性生理学和慢性健康调查（APACHE-II）评分、简化急性生理学评分和医学研究委员会（MRC）脓毒症评分与临床评估以及Ranson和Imrie评分在290例急性胰腺炎发作的评估和监测中的价值进行比较。如果无并发症，则将发作分级为轻度（231）；如果发生主要器官衰竭或胰腺积液，则将发作分级为严重（59）。入院时仅可获得 APACHE-II 分数；他们正确预测了 77% 的发作结果，并识别了 63% 的严重发作，而临床评估的结果为 44%。 48 小时后，APACHE-II 的准确度最高，正确预测了 88% 的攻击结果，而 Ranson 评分为 69%，Imrie 评分为 84%。 APACHE-II 预测 48 小时时胰腺收集量为 73%，而 Ranson 评分为 65%，Imrie 评分为 58%。在急性胰腺炎中，APACHE-II 可能有助于快速选择患者进行强化治疗或临床试验，改善患者组之间的比较，并表明可能存在胰腺积液。
The value of the Acute Physiology and Chronic Health Enquiry (APACHE-II) score, the Simplified Acute Physiology score, and the Medical Research Council (MRC) sepsis score were compared with clinical assessment and Ranson and Imrie scores in the evaluation and monitoring of acute pancreatitis in 290 attacks. Attacks were graded mild (231) if uncomplicated, or severe (59) when major organ failure or a pancreatic collection occurred. Only APACHE-II scores were available at the time of admission; they correctly predicted outcome in 77% of attacks and identified 63% of severe attacks, compared with 44% achieved by clinical assessment. After 48 h, APACHE-II was most accurate, and correctly predicted outcome in 88% of attacks, compared with 69% for Ranson and 84% for Imrie scores. APACHE-II predicted 73% of pancreatic collections at 48 h, compared with 65% for Ranson and 58% for Imrie scores. In acute pancreatitis, APACHE-II may facilitate rapid selection of patients for intensive therapy or clinical trials, improve comparison between groups of patients, and indicate that a pancreatic collection is probable.