Uveitis in Adult Patients with Rheumatic Inflammatory Autoimmune Diseases at a Tertiary-care Hospital in Mexico City
Uveitis in Adult Patients with Rheumatic Inflammatory Autoimmune Diseases at a Tertiary-care Hospital in Mexico City
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DOI：
10.3899/jrheum.100015
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发表时间：
2011-02-01
影响因子：
3.9
通讯作者：
Martinez-Castro, Francisco
中科院分区：
文献类型：
--
作者：
Javier Jimenez-Balderas, Francisco;Fernandez-Arrieta, Gema;Martinez-Castro, Francisco
目标。我们的目的是描述墨西哥城一家三级保健医院风湿科住院的成年患者中与风湿性炎症性自身免疫性疾病(RIAD)相关的葡萄膜炎的频率。我们还描述了该病的临床特征、季节分布、治疗方法和与之相关的眼部并发症。我们回顾了1332例RIAD患者的图表，并选择了那些被诊断为葡萄膜炎的患者。我们获得了以下数据：年龄、性别、葡萄膜炎类型以及与RIAD诊断的关系、复发、季节分布、治疗和残留视力缺陷。在1332份病历中发现葡萄膜炎57例(4.27%)，其中男38例，女19例(男：女2：1)，年龄47±16岁。非肉芽肿性急性前葡萄膜炎(NGAAU)占90.52%(52/57)。在64.91%(37/57)的病例中，葡萄膜炎先于RIAD诊断12+/-9年，冬季更常见(35.96%；p=NS)。强直性脊柱炎(AS)40/93例，复发性多软骨炎(RP)7/11例，白塞病8/16例，结节性多动脉炎1/16例，类风湿关节炎(RA)1/590例。96%的患者接受了类固醇治疗。平均随访60天(范围7-4745天)，视力下降(
Objective. Our aim is to describe the frequency of uveitis associated with rheumatic inflammatory autoimmune diseases (RIAD) in adult patients admitted to the Rheumatology Department at a tertiary-care hospital in Mexico City. We also describe the clinical features, seasonal distribution, treatment, and ocular complications associated with this disease.Methods. We reviewed 1332 charts of patients with RIAD and selected those that had a diagnosis of uveitis. We obtained the following data: age, sex, type of uveitis and relationship with diagnosis of RIAD, recurrences, seasonal distribution, treatment, and residual visual deficit.Results. We found 57 (4.27%) cases of uveitis in 1332 charts, including 38 men and 19 women (M:F ratio 2:1), aged 47 +/- 16 years. Nongranulomatous acute anterior uveitis (NGAAU) comprised 90.52% of cases (52/57). In 64.91% of cases (37/57), uveitis preceded the diagnosis of RIAD by 12 +/- 9 years, more frequently in winter (35.96%; p = NS). Uveitis was found in 40/93 patients with ankylosing spondylitis (AS), in 7/11 patients with relapsing polychondritis (RP), in 8/16 patients with Behcet's disease, in 1/16 patients with polyarteritis nodosa, and in 1/590 patients with rheumatoid arthritis (RA). Ninety-six percent of the patients were treated with steroids. Upon a mean followup of 60 days (range 7-4745 days), reduction of visual acuity (