Four-layer depth-of-interaction PET detector for high resolution PET using a multi-pixel S8550 avalanche photodiode
Four-layer depth-of-interaction PET detector for high resolution PET using a multi-pixel S8550 avalanche photodiode
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DOI：
10.1016/j.nima.2010.03.165
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发表时间：
2010-09-01
影响因子：
1.4
通讯作者：
Murayama, Hideo
中科院分区：
文献类型：
--
作者：
Nishikido, Fumihiko;Inadama, Naoko;Murayama, Hideo
雪崩光电二极管（APD）被用作正电子发射断层扫描（PET）中的光电探测器，因为它们比通常用于PET探测器中的光电倍增管（PMT）具有许多优点。我们开发了一种PET探测器，它由一个多像素APD和一个6 x 6 x 4阵列的1.46 x 1.46 mm（2）x 4.5 m LYSO晶体组成，用于小动物PET扫描仪。该探测器可以识别四层的相互作用深度（DOI）与位置敏感的APD耦合到晶体阵列的背面，只是一个优化的反射器的安排。由于该方法在许多像素之间共享闪烁光，因此远离相互作用晶体的APD像素中的较弱信号受到噪声的影响。为了评估APD四层DOI探测器的性能以及电噪声对我们方法的影响，我们构建了一个原型DOI探测器并测试了它的性能。我们发现，除了晶体阵列边缘的晶体元素，所有的晶体元素都可以从2D位置直方图中识别。整个晶体阵列的APD探测器的能量分辨率为16.9%。探测器性能的噪声依赖性的结果表明，使用APD的DOI探测器可以实现足够的性能，即使在使用专用集成电路。(C)2010 Elsevier BV保留所有权利。
Avalanche photodiodes (APDs) are being used as photodetectors in positron emission tomography (PET) because they have many advantages over photomultipliers (PMTs) typically used in PET detectors. We have developed a PET detector that consists of a multi-pixel APD and a 6 x 6 x 4 array of 1.46 x 1.46 mm(2) x 4.5 m LYSO crystals for a small animal PET scanner. The detector can identify four-layer depth of interaction (DOI) with a position-sensitive APD coupled to the backside of a crystal array by just an optimized reflector arrangement. Since scintillation lights are shared among many pixels by the method, weaker signals in APD pixels far from the interacting crystals are affected by noise. To evaluate the performance of the four-layer DOI detector with the APD and the influence of electrical noise on our method, we constructed a prototype DOI detector and tested its performance. We found, except for crystal elements on the edge of the crystal array, all crystal elements could be identified from the 2D position histogram. An energy resolution of 16.9% was obtained for the whole crystal array of the APD detector. The results of noise dependence of detector performances indicated that the DOI detector using the APD could achieve sufficient performance even when using application-specific integrated circuits. (C) 2010 Elsevier B.V. All rights reserved.