A selective hybrid fluorescent sensor for fructose detection based on a phenylboronic acid and BODIPY-based hydrophobicity probe.
A selective hybrid fluorescent sensor for fructose detection based on a phenylboronic acid and BODIPY-based hydrophobicity probe.
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作者：
果糖广泛用于食品工业。然而，它可能通过产生有害的晚期糖基化终产物而参与疾病。我们设计并合成了一种新型的荧光探针，用于果糖检测，通过结合苯硼酸基团和基于BODIPY的疏水性探针。该探针对果糖浓度在100-1000 μM范围内呈线性响应，检测限为32 μM，可用于果糖的简便、灵敏测定。我们设计并合成了一种新的荧光探针，通过疏水相互作用检测果糖，其检测限为32 μM。
Fructose is widely used in the food industry. However, it may be involved in diseases by generating harmful advanced glycation end-products. We have designed and synthesized a novel fluorescent probe for fructose detection by combining a phenylboronic acid group with a BODIPY-based hydrophobicity probe. This probe showed a linear fluorescence response to d-fructose concentration in the range of 100–1000 μM, with a detection limit of 32 μM, which is advantageous for the simple and sensitive determination of fructose. We have designed and synthesized a novel fluorescent probe for fructose detection through hydrophobic interactions by combining a phenylboronic acid group and a BODIPY-based hydrophobicity probe with a detection limit of 32 μM.
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DOI：
10.1073/pnas.1903949116
发表时间：
2019-07-30
影响因子：
11.1
作者：
Liang, Dongjun;Wu, Kane;Baskin, Jeremy M.
通讯作者：
Baskin, Jeremy M.
影响因子：
7.3
作者：
Jurasek, Michal;Rimpelova, Silvie;Ruml, Tomas
通讯作者：
Ruml, Tomas
影响因子：
3.1
作者：
Buttersack, Christoph
通讯作者：
Buttersack, Christoph
影响因子：
1.6
作者：
Cooper, CR;James, TD
通讯作者：
James, TD
影响因子：
1.8
作者：
DiCesare, N;Lakowicz, JR
通讯作者：
Lakowicz, JR