Functional magnetic resonance imaging evidence for binocular interactions in human visual cortex
Functional magnetic resonance imaging evidence for binocular interactions in human visual cortex
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DOI：
10.1007/s00221-002-1121-x
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发表时间：
2002-08-01
影响因子：
2
通讯作者：
Hennig, J
中科院分区：
文献类型：
--
作者：
B端chert, M;Greenlee, MW;Hennig, J
使用功能磁共振成像（fMRI），我们探索了当受试者观看两眼呈现的棋盘刺激时发生的双眼相互作用。向受试者的每只眼睛呈现闪烁的径向棋盘，同时通过梯度回波、平面回波序列在视觉皮层上获取 T2* 加权图像。我们比较了纹状和纹状外视觉皮层在四种条件下的反应：双眼同时受到刺激（双眼条件）、每只眼睛交替受到刺激（单眼条件）或先刺激一只眼睛，然后刺激另一只眼睛（左眼先-右眼尾随，反之亦然）。结果表明，只有距距裂内部和附近的纹状体区域在这些刺激条件下表现出显着差异。尽管刺激-休息比较中的 BOLD 反应很稳健，但这些差异在更远的纹外或关联视觉区域中并不明显。这些结果表明，这种效应可能与纹状视觉皮层中眼部优势柱的抑制相互作用有关。
Using functional magnetic resonance imaging (fMRI), we explored the binocular interactions occurring when subjects viewed dichoptically presented checker-board stimuli. A flickering radial checkerboard was presented to each eye of the subject, while T2*-weighted images were acquired over the visual cortex with gradient-echo, echoplanar sequences. We compared responses in striate and extrastriate visual cortex under four conditions: both eyes were stimulated at the same time (binocular condition), each eye was stimulated in alternation (monocular condition) or first the one eye then the other eye was stimulated (left eye first - right eye trailing, or vice versa). The results indicate that only the striate area, in and near the calcarine fissure, shows significant differences for these stimulation conditions. These differences are not evident in more remote extrastriate or associational visual areas, although the BOLD response in the stimulation-rest comparison was robust. These results suggest that the effect could be related to inhibitory interactions across ocular dominance columns in striate visual cortex.