Estimation of tumor characteristics in a breast tissue with known skin surface temperature
Estimation of tumor characteristics in a breast tissue with known skin surface temperature
复制标题
在已知皮肤表面温度的情况下估计乳腺组织中的肿瘤特征
DOI：
10.1016/j.jtherbio.2013.04.001
复制
发表时间：
2013
影响因子：
2.7
通讯作者：
S. Mishra
中科院分区：
文献类型：
--
作者：
K. Das;S. Mishra
估计肿瘤的存在及其特征，如位置、大小和特性。估计是基于乳房皮肤表面温度的测量。考虑感染肿瘤的二维乳腺组织。使用 Pennes 生物热方程建模的乳房组织中的传热通过有限体积法求解。乳房皮肤表面温度分布是肿瘤位置、大小和级别的特征。在逆分析中，使用遗传算法最小化目标函数。如果一次估计一个参数，则可以获得精确的估计。然而，即使同时估计血液灌注速率、位置和大小，准确性也是可以接受的。
Presence of a tumor and its characteristics like location, size and properties are estimated. Estimation is based on the measurement of the skin surface temperature of the breast. Consideration is given to a 2-D breast tissue infected with a tumor. Heat transfer in the breast tissue modeled using the Pennes bioheat equation is solved by the finite volume method. Skin surface temperature profile of the breast is characteristic of the tumor location, its size and grade. In the inverse analysis, the objective function is minimized using the genetic algorithm. Exact estimation is obtained if one parameter is estimated at a time. However, the accuracies are acceptable even when blood perfusion rate, location and size are estimated simultaneously.