VENTILATORY RESPONSE TO CO2 DURING WORK AT NORMAL AND AT LOW OXYGEN TENSIONS
VENTILATORY RESPONSE TO CO2 DURING WORK AT NORMAL AND AT LOW OXYGEN TENSIONS
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DOI：
10.1111/j.1748-1716.1957.tb01406.x
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发表时间：
1957-01-01
期刊：
影响因子：
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通讯作者：
NIELSEN, M
中科院分区：
文献类型：
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作者：
ASMUSSEN, E;NIELSEN, M
本文研究了三名受试者在正常和低氧分压下肌肉工作时呼吸中枢对二氧化碳的敏感性。结果发现，在正常空气中，刺激反应曲线的直线部分向静息曲线的左侧移动，且移动得越多，工作强度越高。在大多数情况下，曲线的陡度大致相同。在低氧条件下，刺激-反应曲线比在正常空气中相同的工作强度时更多地向左移动，并且更加陡峭。在较高的二氧化碳浓度下，刺激-反应曲线的平坦被认为主要是由于高二氧化碳对呼吸中枢的一种特殊的抑制作用。
The sensitivity of the respiratory center to CO2during muscular work at normal and at low oxygen tensions has been studied in three human subjects.It was found that the rectilinear part of the stimulus‐response curves in normal air was displaced to the left of the resting curve and the more so the higher the work intensity. The steepness of the curves was in the majority of cases about the same. In low oxygen the stimulus‐response curves were displaced more to the left and were much steeper than for the same work intensity in normal air. The flattening of the stimulus‐response curves found at higher CO2concentrations is assumed to be due mainly to a special depressant effect of high CO2tensions on the respiratory center.