The minimum information about a proteomics experiment (MIAPE)

The minimum information about a proteomics experiment (MIAPE)
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DOI:
10.1038/nbt1329
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发表时间:
2007-08-01
影响因子:
46.9
通讯作者:
Hermjakob, Henning
Hermjakob, Henning
中科院分区:
工程技术1区
文献类型:
--
作者:
Taylor, Chris F.;Paton, Norman W.;Hermjakob, Henning

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现在,蛋白质组学数据的生成和分析都是广泛的,高通量方法很普遍。随着方法和技术的发展和多样化,协议继续增加复杂性。为了鼓励人类蛋白质组学组织的蛋白质组学标准计划的标准化收集,集成,存储和传播蛋白质组学数据,开发了用于报告使用凝胶电泳和质谱等技术的指导模块。本文描述了这些模块发展的过程和原则。讨论了各种利益集团的后果,例如实验家,资助者,出版商和私营部门;解决与其他报告指南重叠的问题;并强调了适当的工具和资源的关键,以实现“符合MIAPE的”报告。
Both the generation and the analysis of proteomics data are now widespread, and high-throughput approaches are commonplace. Protocols continue to increase in complexity as methods and technologies evolve and diversify. To encourage the standardized collection, integration, storage and dissemination of proteomics data, the Human Proteome Organization's Proteomics Standards Initiative develops guidance modules for reporting the use of techniques such as gel electrophoresis and mass spectrometry. This paper describes the processes and principles underpinning the development of these modules; discusses the ramifications for various interest groups such as experimentalists, funders, publishers and the private sector; addresses the issue of overlap with other reporting guidelines; and highlights the criticality of appropriate tools and resources in enabling 'MIAPE-compliant' reporting.