The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
The Significance of the Effect of Visceral Adiposity on Left Ventricular Diastolic Function in the General Population
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DOI：
10.1038/s41598-018-37137-x
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发表时间：
2019-03
影响因子：
4.6
通讯作者：
Naoko Sawada;M. Daimon;T. Kawata;Tomoko Nakao;Koichi Kimura;Koki Nakanishi;M. Kurano;M. Hirokawa;Boqing Xu;Y. Yamanaka;T. Kato;Masafumi Watanabe;Y. Yatomi;I. Komuro
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文献类型：
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作者：
Naoko Sawada;M. Daimon;T. Kawata;Tomoko Nakao;Koichi Kimura;Koki Nakanishi;M. Kurano;M. Hirokawa;Boqing Xu;Y. Yamanaka;T. Kato;Masafumi Watanabe;Y. Yatomi;I. Komuro
我们评估了213名无明显心脏病的受试者的内脏脂肪和左心室舒张功能与血浆脂联素水平之间的关系。腹部内脏脂肪面积通过计算机断层扫描量化。过多的内脏脂肪与E/A、E′和E/E′等舒张参数受损显著相关。尽管血清脂联素水平随着内脏脂肪的增加而下降，但血清脂联素水平与舒张参数之间没有独立的关联，这表明脂联素在这种关联中的作用可能是间接的。
We evaluated the association between visceral adiposity and left ventricular (LV) diastolic function in association with plasma adiponectin levels in 213 subjects without overt cardiac diseases. Abdominal visceral fat area was quantified by computed tomography. Excessive visceral fat was significantly associated with impaired diastolic parameters including E/A, E′ and E/E′. Although serum adiponectin levels decreased with increased visceral adiposity, there was no independent association between serum adiponectin levels and diastolic parameters, which suggest that the role of adiponectin in this association might be indirect.