Oxytocin increases gaze to the eye region of human faces
Oxytocin increases gaze to the eye region of human faces
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DOI：
10.1016/j.biopsych.2007.06.026
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发表时间：
2008-01-01
影响因子：
10.6
通讯作者：
Dadds, Mark R.
中科院分区：
文献类型：
--
作者：
Guastella, Adam J.;Mitchell, Philip B.;Dadds, Mark R.
背景：在非人类哺乳动物中，催产素在同伴识别和社交行为中起着至关重要的作用。在人类中，催产素被发现可以增强信任和解释他人情绪的能力。有人提出，催产素可以通过增加对人脸眼部区域的关注来增强面部处理。方法：在双盲、随机、安慰剂对照、受试者间设计中，我们跟踪了 52 名健康男性志愿者的眼球运动，这些志愿者在鼻内施用 24 IU 催产素或安慰剂后呈现 24 张中性人脸。结果：与对照组相比，给予催产素的参与者表现出对眼部区域的注视次数和总凝视时间增加。安慰剂参与者。结论：催产素会增加对人脸眼部区域的注视。这可能是催产素增强人类情绪识别、人际沟通和社交行为的一种机制。研究结果表明，催产素在治疗以目光回避和面部处理缺陷为特征的疾病中可能发挥作用。
Background: In nonhuman mammals, oxytocin has a critical role in peer recognition and social approach behavior. In humans, oxytocin has been found to enhance trust and the ability to interpret the emotions of others. It has been suggested that oxytocin may enhance facial processing by increasing focus on the eye region of human faces.Methods: In a double-blind, randomized, placebo-controlled, between-subject design, we tracked the eye movements of 52 healthy male volunteers who were presented with 24 neutral human faces after intranasal administration of 24 IU oxytocin or placebo.Results: Participants given oxytocin showed an increased number of fixations and total gaze time toward the eye region compared with placebo participants.Conclusions: Oxytocin increases gaze specifically toward the eye region of human faces. This may be one mechanism by which oxytocin enhances emotion recognition, interpersonal communication, and social approach behavior in humans. Findings suggest a possible role for oxytocin in the treatment of disorders characterized by eye-gaze avoidance and facial processing deficits.